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DeCS
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Descriptor English:
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Tumor Suppressor Protein p14ARF
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Descriptor Spanish:
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Proteína p14ARF Supresora de Tumor
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Descriptor Portuguese:
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Proteína Supressora de Tumor p14ARF
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Synonyms English:
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p14ARF Protein
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Tree Number:
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D12.776.167.600
D12.776.624.776.772
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Definition English:
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A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PROTEIN (which regulates P53 TUMOR SUPPRESSOR PROTEIN by targeting it for degradation). p14ARF is produced from the beta mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced alpha transcript, is CYCLIN-DEPENDENT KINASE INHIBITOR P16. Both p16 gene products have tumor suppressor functions. |
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See Related English:
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Cyclin-Dependent Kinase Inhibitor p16
Genes, p16
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History Note English:
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2002(1996)
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Allowable Qualifiers English:
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Record Number:
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36196
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Unique Identifier:
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D025803
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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